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Abstract #3583

Reliability of Bi-Exponential Parameter Estimation

Koichi Oshio1

1Department of Diagnostic Radiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan


The shape of bi-exponential fitting errors in the parameter space was calculated and visualized. From these plots, it is suggested that parameter estimation with bi-exponential curve fitting is not reliable, even thtough the fitting itself is good, especially for small range of b-value. Using a new set of parameters, D and d, it is possible to estimate the parameters more reliably, and the parameter interpretation becomes more straightforward.