Wei Feng1, E Mark Haacke1, 2
1Radiology, Wayne State University, Detroit, MI, United States; 2Biomedical Engineering, Wayne State University, Detroit, MI, United States
Two-dimensional spatially selective RF pulse design evolved from investigation under the small-tip-angle (STA) assumption to general design without such a constraint, using either least squares optimization or an optimal control approach. Most work focused on optimization of the RF waveform given a fixed gradient trajectory. In this work, we propose a RF and gradient joint design algorithm under the framework of optimal control theory using a cubic B-spline waveform model. Preliminary results show that the algorithm can improve the excitation profile over the design under the STA assumption, especially for large tip angles.