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Abstract #1925

DSI Motion Correction and Thalamo-Cortical Fiber Pathway Alteration After Stroke

Young Beom Kim1, 2, Chrystelle Po2, Daniel Kalthoff2, Mathias Hoehn2

1Advanced Media Lab, SAIT, Yongin, Gyeonggi, Korea, Republic of; 2In-Vivo-NMR Lab, Max-Planck-Institute for Neurological Research, Cologne, Germany


Fiber tracking in small laboratory animals is of great interest as it is expected to open doors to understanding connectivity in controlled paradigms which can also be assessed with independent means. These fiber tracking investigations have been performed using DTI because of the demand to combine high resolution, low signal-to-noise of small voxels, and speed of scan time for minimization of anesthesia period. Diffusion spectrum imaging provides a more complex analysis of fiber circuits than the so far used DTI approach, discriminating also crossing fibers in the brain.