Highly Accelerated Parallel 1H MRSI at 7T with Simultaneous Suppression of Near- And Far-Reaching Signal Leakage

Thomas Kirchner¹, Ariane Fillmer¹, Peter Boesiger¹, Klaas Paul Pruessmann¹, Anke Henning¹

We tailor the SENSE reconstruction algorithm towards accelerated parallel MRSI at ultra-high field strengths. Through calculation on an overdiscretized spatial grid and careful tuning of the spatial response function we achieve efficient suppression of signal contaminations caused by voxel bleeding without the increase of the effective voxel size that would be caused by conventional filtering techniques. We demonstrate up to 9-fold accelerated proton MRSI in vivo at 7T.