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Abstract #1725

Spectroscopic Imaging of Glycine of Human Brain at 7.0 T

Sandeep K. Ganji1, 2, Abhishek Banerjee1, Elizabeth Maher3, 4, Changho Choi1, 2

1Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States; 2Radiology, University of Texas Southwestern Medical Center, Dallas, TX, United States; 3Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, United States; 4Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, United States


In Vivo spectroscopic imaging of Gly is challenging due to its low concentrations and the spectral overlap, primarily with myo-inositol. By going to higher field strengths this situation can improve due to increased spectral resolution. We employed an optimized chemical shift imaging method for glycine imaging at 7T and present preliminary data from healthy volunteers and tumor patients.