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Abstract #1515

Visualization of Prostate Fibromuscular Stromal Matrix Using Ex-Vivo High-Resolution DTI Tractography

Nyoman D. Kurniawan1, Gary Cowin1, Paul Sved2, Geoffery Watson3, Roger Bourne4

1Centre for Advanced Imaging, University of Queensland, Brisbane, Queensland, Australia; 2Department of Urology, Royal Prince Alfred Hospital, The University of Sydney, Sydney, New South Wales, Australia; 3Department of Anatomical Pathology, Royal Prince Alfred Hospital, University of Sydney, Sydney, New South Wales, Australia; 4Discipline of Medical Radiation Sciences, Faculty of Health Sciences, The University of Sydney, Sydney, New South Wales, Australia


16.4T high-resolution diffusion tensor imaging (DTI) of fixed prostate cancer biopsy has revealed distinct microscopic diffusion environments and tissue architecture consistent with that seen on light microscopy. In this study, we present a new methodology for the visualization of fibromuscular stromal matrix from a prostate biopsy using high-resolution DTI-tractography.