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Abstract #1380

Quantification of Longitudinal Changes in Cartilage Following Viscosupplementation Therapy Via T1ρ MRI

Matthew Fenty MBA1, Roshan Shah MD JD2, Yinan Kuang3, Jeff Stambough MD2, John Kelly MD4, Ravinder Reddy PhD1, Fotios Tjoumakaris MD5

1Center for Magnetic Resonance and Optical Imaging, University of Pennsylvania, Philadelphia, PA, United States; 2McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, United States; 3School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, PA, United States; 4Sports Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, United States; 5Sports Medicine, Rothman Institute, Egg Harbor Township, NJ, United States


Ten subjects who presented clinically with Kellgren-Lawrence grade 1 or 2 osteoarthritis were imaged using T MRI following routine treatment using Hylan G-F 20 viscosupplementation. Quantitative assessments of cartilage health was analyzed prior to VS, 6 weeks post-, and 3 months post-surgery to examine effects of VS within the joint.