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Abstract #1344

Oxygen Enhanced Lung MRI Using 3D Radial UTE SPGR in Humans

Stanley J. Kruger1, Kevin M. Johnson1, Sean B. Fain1, 2, Robert V. Cadman1, Laura C. Bell1, Scott K. Nagle1, 3

1Medical Physics, University of Wisconsin, Madison, WI, United States; 2Biomedical Engineering, University of Wisconsin, Madison, WI, United States; 3Radiology, University of Wisconsin, Madison, WI, United States


Oxygen Enhanced MRI of lung parenchyma has so far relied on a SSFSE sequence paired with an inversion recovery to mitigate T2* decay and provide ample contrast in the low signal environment. Coverage is often limited, and multiple acquisitions are required to obtain adequate SNR. Radial 3D UTE-SPGR is a new technique in oxygen enhanced MRI that combines oversampling the center of k-space as well as short TE to yield a 3D isotropic volume of oxygen enhanced signal that is robust against cardiac motion artifact and T2* decay, while providing full lung coverage in any orientation.