Two Lipid Pools Detected in the Myocardium of Rats Fed a High
Fat Diet
Vijayasarathi Nagarajan1, Philip William
Kuchel1, S. Sendhil Velan1
1Laboratory of Molecular Imaging,
Singapore Bioimaging Consortium, Singapore, Singapore
We evaluated
the myocardial fat content in rats fed with a placebo and a high fat diet.
We demonstrated the presence of two lipid pools in the myocardium of the rats
with obesity induced by high fat diet. The left ventricular function was
significantly reduced in rats fed with high fat diet. The concentration of
IMCL in myocardium may be a potential marker for early stages of diabetes.
