Sumei Wang1, Ronald L. Wolf1, Edward B. Lee2, Harish Poptani1, Elias R. Melhem1, John YK Lee3, Sungheon Kim4
1Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, United States; 3Neurosurgery, University of Pennsylvania, Philadelphia, PA, United States; 4Radiology, New York University School of Medicine, New York, NY, United States
The purpose of this study is to determine whether permeability and rCBV measurements can help in determining the histologic grade and subtypes of meningiomas. Thirty-one meningiomas underwent DSC studies. All the perfusion parameters including corrected rCBV, uncorrected rCBV, Ktrans, Ve and Vp were measured from the enhancing part of the tumor. Our result showed that corrected rCBV is helpful in differentiating atypical from typical meningiomas, whereas Ktrans and Ve measurements are useful in distinguishing different subtypes of meningiomas.