Abstract #0846

Contrast Leakage in High Grade Glioma Measured with Independent Component Analysis of Dynamic Susceptibility Contrast MRI

Peter S. LaViolette¹, Alex D. Cohen², Kathleen M. Schmainda,¹²

¹Radiology, Medical College of Wisconsin, Milwaukee, WI, United States; ²Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States

This study measures the difference between the two separate contrast agent boluses in patients with high-grade glioma using regions of interest (ROIs) defined by a novel unbiased independent component analysis (ICA) approach.