Yoshiharu Ohno1, 2, Mizuho Nishio1, Hisanobu Koyama1, 2, Takeshi Yoshikawa1, Sumiaki Matsumoto1, Daisuke Takenaka1, Katsusuke Kyotani2, Nobukazu Aoyama2, Hideaki Kawamitsu2, Makoto Obara3, Marc van Cauteren4, Kazuro Sugimura1
1Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; 2Radiology, Kobe University Hospital, Kobe, Hyogo, Japan; 3Philips Electronics Japan, Tokyo, Japan; 4Philips Healthcare Asia Pacific, Tokyo, Japan
O2-enhanced MRI can assess regional ventilation and alveolocapillary gas transfer of molecular oxygen. However, none of these studies have examined the quantitative and qualitative capabilities of O2-enhanced MRI for evaluation of candidates for lung volume reduction surgery (LVRS), and compared with that of evaluation by means of thin-section MDCT and perfusion SPECT/CT. The purpose of the study was thus to prospectively and directly compare the quantitative and qualitative capabilities of O2-enhanced MRI, thin-section MDCT and perfusion SPECT/CT to predict therapeutic outcomes for LVRS candidates.