Manojkumar Saranathan1, Dan W. Rettmann2, Brian A. Hargreaves3, Jafi Lipson3, Bruce Daniel3
1Radiology, Stanford University, Stanford, CA , United States; 2Global Applied Science Laboratory, GE Healthcare, Rochester, MN, United States; 3Radiology, Stanford University, Stanford, CA, United States
Dynamic-contrast enhanced (DCE) MRI is the primary approach for clinical breast imaging but is beset by the need for both high spatial and high temporal resolution [1-2], often resulting in suboptimal compromises. High temporal resolution is required for quantitative pharmacokinetic modeling whereas high spatial resolution is necessary for clear delineation of tumor morphology. We present clinical results from 20 patients of a new variable spatio-temporal resolution technique that seamlessly switches between the high temporal and high spatial resolution modes. Bilateral coverage with 0.9x0.9x1.2 mm spatial resolution was achieved, with the two modes having a temporal resolution of ~9s and ~120s respectively