Abstract #0439

Time-Resolved Phosphorous Magnetization Transfer of the Human Calf Muscle at 3T & 7T: A Feasibility Study

Ladislav Valkovic¹,², Marek Chmelik¹, Ivica Just Kukurova¹, Martin Krk³, Stephan Gruber¹, Ivan Frollo⁴, Siegfried Trattnig¹, Wolfgang Bogner¹

¹MR Centre of Excellence, Department of Radiology, Medical University of Vienna, Vienna, Austria; ²Department of Imaging Methods, Institute of Measurement Science, Slovak Academy of Sciences , Bratislava, Slovakia; ³Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; ⁴Department of Imaging Methods, Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovakia

The aim of this study was to compare precision of magnetization transfer (MT) experiments at 3T&7T and to analyze the potential time resolution of MT at 7T. Calf muscles of six healthy subjects were consecutively measured on two MR scanners (3T&7T). The MT protocol was split to four parts (each 10min 36sec) to compare the variability of repeated measurements and to test time resolved MT experiments. No MT experiments of the skeletal muscle have been performed as yet at 7T. We were able to show that the time-resolved MT in the muscle with ~10min temporal resolution is feasible at 7T.