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Abstract #0234

SSAT Inducer as a Potential Treatment for Obesity-Related Heart Failure

Jun Lu1, Mingming Li2, Beau Pontre3, Stephen Pickup4, Anothny Phillips2, Garth JS Cooper2

1Faculty of Health & Environmental Sciences, Auckland University of Technology, Auckland, North Island, New Zealand; 2School of Biological Sciences, University of Auckland, Auckland, New Zealand; 3Centre for Advanced MRI, University of Auckland, Auckland, New Zealand; 4Dept of Radiology, University of Pennsylvania, Philadelphia, PA, United States


This project uses High-Field MRI to study cardiac function and body fat composition of obese mice and the effects of the treatment by diethylnorspermidine, a potent inducer of spermidine/spermine acetyltransferase