Abstract #0156

Three-Dimensional First-Pass Cardiac Perfusion MRI Using a Stack-Of-Spirals Aquisition

Taehoon Shin¹, Krishna S. Nayak², Juan M. Santos³, Dwight G. Nishimura¹, Bob S. Hu,³⁴, Michael V. McConnell⁵

¹Electrical Engineering, Stanford University, Stanford, CA, United States; ²Electrical Engineering, University of Southern California, Los Angeles, CA, United States; ³Heart Vista Inc., Palo Alto, CA, United States; ⁴Palo Alto Medical Foundation, Palo Alto, CA, United States; ⁵Cardiovascular Medicine, Stanford University, Stanford, CA, United States

Three-dimensional first-pass myocardial perfusion imaging (MPI) has shown great promise for precise sizing of defects and for providing high perfusion contrast. It remains an experimental approach primarily due to poor spatial resolution and issues with motion. We have developed a rapid 3D MPI method using a stack-of-spirals acquisition accelerated by k-t SENSE, which allows whole-heart coverage with 2.4x2.4x9 mm³ spatial resolution. This approach correlates well with standard 2DFT method in terms of overall temporal dynamics and upslope of time intensity curves.