Qin Chen1, Pinglei Pan1, Wei Song1, Hehan Tang2, Dong Zhou1, Qiyong Gong2, Huifang Shang1
1Department of Neurology, West China Hospital of Sichuan University, Chengdu, Sichuan, China; 2Department of Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
Recent studies have applied functional MRI to investigate the altered brain function on PD patients[2,3], but it still remains unclear about how the neural network changes in different stages of PD. The present study aims to examine alterations pattern of regional and neural network function in PD patients in different stages by using resting state fMRI. The result indicated that a complementary hyperactivity neural network in the early stage shifted to a normal level or even decreased function in the late stage in patients with PD.