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Abstract #4672

Diffusion Kurtosis Imaging In Vivo; from Basics to Clinical Applications.

Masaaki Hori1, Yoshitaka Masutani2, Ryo Sato3,4, Koji Kamagata3, Koichi Asahi3, Nozomi Hamasaki3, Shuji Satou3, Atsushi Nakanishi3, Keigo Shimoji3, Haruyoshi Houshito3, Ryohei Kuwatsuru3, Keisuke Sasai3, Masaru Takashima5, Yuriko Suzuki5, Shigeki Aoki3

1Radiology, School of Medicine, Juntendo University, Tokyo, Japan; 2Radiology, TheUniversity of Tokyo Hospital, Tokyo, Japan; 3Radiology, School of Medicine, Juntendo University, Tokyo, Japan; 4Radiological Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan; 5Philips Electronics Japan, Tokyo, Japan


The purpose of this exhibit is to present the basics of diffusion kurtosis imaging (DKI), normal DKI atlas of the brain, and to discuss clinical usefulness. DKI is recently developed technique that characterizes non-Gaussian water diffusion, which are different from conventional diffusional metrics, such as fractional anisotropy (FA). In some clinical situations, DKI has showed better results, compared with conventional FA or apparent diffusion coefficient investigation. This technique has potential to provide new and additional information to conventional diffusional metrics in routine clinical study.