Abstract #4425

Theoretical & Experimental Efficiency & Optimization of Flip Angle Mapping Techniques

Trevor Wade^1,2, Charles McKenzie^2,3, Brian Rutt⁴

¹Robarts Research Institute, London, Ontario, Canada; ²Biomedical Engineering, the University of Western Ontario, London, Ontario, Canada; ³Medical Biophysics, the University of Western Ontario, London, Ontario, Canada; ⁴Department of Radiology, Stanford University, Stanford, CA, United States

A theoretical propagation of noise analysis was conducted on 3 flip angle (α) imaging techniques (the saturated double angle method, actual flip angle imaging, and the non-inverted double angle Look-Locker method). This analysis was used to predict the optimal imaging parameters, and the imaging efficiency (α to α noise ratio (ANR) normalized by scan time). The predicted ANR was then compared to the experimentally measured value for a range of flip angles and T1 values.