Abstract #4298

Magnetic Resonance Spectroscopy of Human Cervical Spondylosis at 3T

Rajakumar Nagarajan¹, Michael Albert Thomas¹, Benjamin M. Ellingson¹, Langston Holly², Noriko Salamon¹

¹Radiological Sciences, University of California Los Angeles, Los Angeles, CA, United States; ²Neurosurgery, University of California Los Angeles

Cervical spondylosis is a general term for age-related wear and tear affecting the joints in the neck. Proton (1H) magnetic resonance spectroscopy (MRS) has been widely used over the last few years to differentiate metabolic changes associated with neurological disease in the brain. This present study attempts to quantitate metabolites in cervical spine using point resolved spectroscopy (PRESS) on a 3T MRI scanner processed by the LC model software. Our preliminary results show significantly increased total choline, and increasing trend of lactate (Lac) and decreasing trend of N-acetylaspartate (NAA) in the spondylosis patient group.