Isotropic Multispectral QMRI with the Mixed-TSE Pulse Sequence & SENSE: Implications for Synthetic-MRI

Stephan William Anderson¹, Osamu Sakai¹, Memi Watanabe¹, Jorge A. Soto¹, Hernan Jara¹

Purpose: To develop a pulse sequence for isotropic multispectral (PD, T1, T2) qMRI with clinically compatible scan times. Methods: A variant of the mixed turbo spin echo pulse sequence with parallel imaging (SENSE) and with true isotropic spatial resolution (voxel=1.25mm3) was implemented at 3T. Results: Isotropic volumetric PD, T1, and T2 maps were generated and used for synthetic MRI. Conclusion: Isotropic multispectral qMRI is feasible in clinically compatible times allowing for accurate multiplanar qMRI and synthetic MRI.