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Abstract #4210

Understanding Evolution of Neurocysticercosis through Diffusion Tensor Imaging

Rakesh Kumar Gupta1, Bharti Anand1, Rishi Awasthi1, Ram K. S. Rathore2, Richa Trivedi3, Vimal Kumar Paliwal4, Kashi Nath Prasad5

1Radiodiagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India; 2Mathematics & Statistics, Indian Institute of Technology, Kanpur, Kanpur, Uttar Pradesh, India; 3Institute of Nuclear Medicine and Allied Sciences, New Delhi, Uttar Pradesh, India; 4Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India; 5Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India


Diffusion tensor imaging (DTI) was performed on 25 neurocysticercosis (NCC) patients to look for any changes in DTI measures during the evolutionary course of NCC lesions from vesicular to calcified stage in the brain. A total 90 cyst were studied in 25 cases. DTI measures from NCC were calculated in different stages of evolution in all cases. Successive decrease in apparent diffusion coefficient (ADC) and spherical anisotropy (CS) values and increase in fractional anisotropy (FA), linear anisotropy (CL) and planer anisotropy (CP) values was observed, moving from vesicular to nodular calcified stage. We conclude that DTI measures vary in different stages of evolution of NCC and may be of some value in its characterization