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Abstract #4166

Differential Brain Activation Associated with the Effects of Emotional & Non-Emotional Distracters During a Delayed-Response Working Memory Task in Patients with Schizophrenia

Gwang-Won Kim1, Moo-Suk Lee2, Heoung-Keun Kang3, Tae-Jin Park4, Young-Chul Chung5, Jong-Chul Yang5, Gyung-Ho Chung6, Gwang-Woo Jeong1,3

1Interdisciplinary Program of Biomedical Engineering, Chonnam National University Medical School, Gwangju, Chonnam, Korea, Republic of; 2Psychiatry, Chonnam National University Hospital, Korea, Republic of; 3Radiology, Chonnam National University Hospital, Korea, Republic of; 4Psychology, Chonnam National University, Korea, Republic of; 5Psychiatry, Chonbuk National University Hospital, Korea, Republic of; 6Radiology, Chonbuk National University Hospital, Korea, Republic of


Impairment of working memory (WM) is an important factor of the cognitive deficits in patients with schizophrenia. Dysfunction of the dorsolateral prefrontal cortex (DLPFC) closely related to delayed-response WM is potentially involved with cognitive impairment of the WM observed in schizophrenia patients.