Abstract #4146

Effect of RTMS on Cerebello-Thalamo-Cortical Connectivity in Essential Tremor

Ccile Gallea¹, La Marais¹, Traian Popa¹, David Grabli^2,3, Emmanuel Roze^2,3, Vincent Perlbarg⁴, David Coynel⁴, Bertrand Degos^2,3, Marie Vidailhet^2,3, Stphane Lehricy^1,2, Sabine Meunier^2,3

¹Centre for Neuroimaging Research - CENIR, Paris, Piti-Salptrire Hospital, France; ²Centre de Recherche de l'Institut du Cerveau et de la Moelle Epinire, UPMC - INSERM UMR S975 - CNRS UMR 7225; ³Fdration des Maladies du Systme Nerveux, AP-HP Groupe Hospitalier Piti-Salptrire, Paris; ⁴Laboratoire d'Imagerie Fonctionnelle, INSERM - UPMC - UMR S678

Essential tremor (ET) is a movement disorder involving cerebellar dysfunction. This study aimed at evaluating the effect of cerebellar repetitive magnetic transcranial stimulation (rTMS) during five days on the fMRI functional connectivity in the sensorimotor network (SMN)in ET patients.