Abstract #4038

3D Cine Phase-Contrast MRI of Flow Patterns & Turbulent Kinetic Energy in Patient-Specific Models of Carotid Disease Under in Vivo Mimicking Flow Conditions

Petter Dyverfeldt^1,2, Gabriel Acevedo-Bolton¹, Alastair J. Martin¹, David Saloner¹

¹Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States; ²CMIV & Linkping University, Linkping, Sweden

This study demonstrates the potential of using 3D cine PC-MRI in patient-specific models of atherosclerotic carotid disease to provide detailed information of flow patterns and the spatiotemporal dynamics of turbulence intensity. 45 minutes long high-resolution 3D cine PC-MRI scans were performed in patient-specific models of carotid disease under in-vivo mimicking flow conditions. These high-quality MR data permitted visualization and analysis of potential transarterial pathways for emboli, intrastenotic flow features, and the destabilizing effects of flow deceleration.