Look-Locker 3D-EPI ASL at 7T

Emma Louise Hall¹, Penny A. Gowland¹, Susan T. Francis¹

Look-Locker ASL provides a technique for the simultaneous assessment of transit time for accurate assessment of perfusion. However, due to the limited time between readout pulses volume coverage of this method is generally limited to a few slices. Here we implement LL-FAIR combined with a 3D-EPI readout at 7T. We show that 3D-EPI provides a significant increase in the number of slices that can be acquired due to parallel imaging along two directions, improved SNR and identical perfusion weighting across all slices. This allows a larger volume coverage without compromising on the temporal or spatial resolution.