Andreas P. Arnoldi1, Michael Ingrisch2,
Sandra Utzschneider3, Maximilian F. Reiser1, Sabine
Weckbach1
1Department of Clinical
Radiology, Ludwig-Maximilians-University Munich, Munich, Bavaria, Germany; 2Josef
Lissner Laboratory, Department of Clinical Radiology,
Ludwig-Maximilians-University Munich, Munich, Germany; 3Department
of Orthopedics, Campus Grosshadern, Ludwig-Maximilians-University Munich,
Munich, Germany
Our study on perfusion quantification in 6 patients with OCD lesions of the knee and talus using a two compartment model shows the feasibility of DCE-MRI to detect lesions in patients with OCD and to quantify perfusion and permeability. This quantitative approach showing elevated perfusion and permeability parameters provides additional information on the pathophysiology of OCD, might influence disease management and provide a non-invasive tool for therapy monitoring.