Junichi Tokuda1, Kemal Tuncali1,
Iulian Iordachita2, Sang-Eun Song1, Andriy Fedorov1,
Sota Oguro1, Andras Lasso3, Fiona M. Fennessy1,
Yi Tang1, Clare M. Tempany1, Nobuhiko Hata1
1Department of Radiology, Brigham
& Women's Hospital, Boston, MA, United States; 2The Johns
Hopkins University, Baltimore, MD, United States; 3School of
Computing, Queen's University, Kingston, ON, Canada
This paper reports our initial feasibility study of MRI-guided core needle biopsy of the prostate in a 70cm bore 3-Tesla MRI scanner. Biopsy targets were defined on an intra-procedural T2 image as well as pre-operative MR images registered to the intra-procedural T2 image prior to the needle placement. The needle was guided by a specially-designed needle guidance grid template, which was registered to the image coordinate system by a z-shaped calibration frame. Our clinical study on 5 patients demonstrated that the procedure was feasible with needle placement accuracy of 4.9 mm.