Cerebral Arterial & Venous Blood Volume Changes During the Post-Stimulus BOLD Undershoot Period

Tae Kim¹, Soeng-Gi Kim¹

Sources of post-stimulus BOLD undershoots were investigated by measuring cerebral arterial and venous blood volume changes in isoflurane-anesthetized cats. After the cessation of 40-s visual stimulation, arterial CBV showed post-stimulus undershoots, similar to BOLD, while venous CBV returned to baseline slowly. Both CBF undershoot (due to arterial CBV undershoot) and slow venous CBV return contribute to the post-stimulus BOLD undershoot