Abstract #3520

Simultaneous Bloch-Siegert B1 Mapping & Imaging of Hyperpolarized Pyruvate, Bicarbonate, & Lactate, in a Single Tracer Bolus

Angus Zoen Lau^1,2, Albert P. Chen³, Charles H. Cunningham^1,2

¹Medical Biophysics, University of Toronto, Toronto, ON, Canada; ²Imaging Research, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; ³GE Healthcare, Toronto, ON, Canada

Precise determination of transmit RF power (B₁⁺) for ¹³C MR is challenging due to limited natural abundance of ¹³C in vivo. The phase-based Bloch-Siegert shift provides a B₁ mapping method independent of M_z, making it possible to encode B₁ in an image of hyperpolarized magnetization.