Evaluation of B0-Inhomogeneity Correction for Triple-Quantum-Filtered Sodium MRI of the Human Brain at 4.7T

Adrian Tsang¹, Rob Stobbe¹, Christian Beaulieu¹

B0-inhomogeneities may cause regional signal loss on triple-quantum-filtered (TQF) sodium images. Three phase cycling algorithms were proposed recently to rectify this adverse effect with the cost of extensively increasing scan time; however, these were all only verified on small agarose phantoms. The goal of our study is to evaluate the extent of off resonance signal loss and their correction on human brain sodium TQF images and to determine whether the considerable two fold increase in scan time is warranted for in vivo studies.