Christopher John Evans1, Frederic Boy1,
Richard A. E. Edden2,3, Krish D. Singh1, Masud Husain4,
Petroc Sumner1
1CUBRIC, School of
Psychology, Cardiff University, Cardiff, Wales, United Kingdom; 2Russell
H. Morgan Department of Radiology & Radiological Science, the Johns
Hopkins University, Baltimore, United States; 3F.M. Kirby Research
Center for Functional MRI, Kennedy Krieger Institute, Baltimore, United
States; 4UCL Institute of Cognitive Neuroscience & UCL
Institute of Neurology, UCL, London, England, United Kingdom
The concentration of inhibitory neurotransmitter GABA has previously been demonstrated to predict participants performance in visual behavioural tasks. Here, we demonstrate that GABA concentration correlates with the performance of participants in a motor task closely associated with behavioural inhibition (the Negative Compatibility Effect, NCE). Individual differences in participants' NCE is explained by differences in participants GABA levels in the supplementary motor area, but not correlated with other brain regions.