Eugene Ozhinsky1,2, Adam B. Kerr3,
Sarah J. Nelson1,4
1Surbeck Laboratory of Advanced
Imaging, Department of Radiology & Biomedical Imaging, University of
California, San Francisco, San Francisco, CA, United States; 2UCSF/UCB
Joint Graduate Group in Bioengineering, University of California, San
Francisco; 3Department of Electrical Engineering, Stanford
University, CA, United States; 4Department of Bioengineering &
Therapeutic Sciences, University of California, San Francisco
A protocol with automated prescription has been developed for 3D spectroscopic imaging of the brain. Automatic placement of an oblique excitation slice and outer-volume suppression (OVS) bands instead of PRESS localization allowed for a fast prescription including full brain coverage. The use of novel dualband very-selective suppression (VSS) pulses shortened the length of the saturation pulse train and helped achieve sharper transition bands, compared to the existing nonlinear-phase single-band VSS pulses.