Abstract #3441

In Vivo T2 of GABA at 7T: Measuring Transverse Relaxation Times using Edited MRS

Jarunee Intrapiromkul¹, Ying Cheng², He Zhu^1,3, Peter B. Barker^1,3, Richard Anthony Edward Edden^1,3

¹Russell H. Morgan Department of Radiology & Radiological Science, the Johns Hopkins University, Baltimore, MD, United States; ²Department of Biomedical Engineering, the Johns Hopkins University, Baltimore, MD, United States; ³Kennedy Krieger Institute, Baltimore, MD, United States

Accurate measurement of in vivo relaxation times is necessary for quantitative in vivo magnetic resonance spectroscopy. Recent work applying edited MRS of GABA has generally quoted concentrations in institutional units or as signal ratios, in part because the in vivo relaxation times of GABA are unknown. In this abstract, we characterize the TE-dependence of edited GABA detection at 7T and show that this knowledge allows T2 to be measured (T2 = 53 ms).