Abstract #3364

Left Ventricular Volumes, Mass & Function Normalized to the Body Surface Area, Age & Gender from CMR in a Large Cohort of Well-Treated Thalassemia Major Patients Without Myocardial Iron Overload.

Antonella Meloni¹, Maria Chiara Dell'Amico¹, Brunella Favilli¹, Giovanni Donato Aquaro¹, Pierluigi Festa¹, Elisabetta Chiodi², Stefania Renne³, Gennaro Restaino⁴, Vincenzo Positano¹, Maria Concetta Galati⁵, Massimo Lombardi¹, Alessia Pepe¹

¹Fondazione G.Monasterio CNR-Regione Toscana & Institute of Clinical Physiology, Pisa, Italy; ²Arcispedale S. Anna, Ferrara, Italy; ³P.O. Giovanni Paolo II, Lamezia Terme, Italy; ⁴Universit Cattolica del Sacro Cuore, Campobasso, Italy; ⁵A.O. "Pugliese-Ciaccio", Catanzaro, Italy

Cardiovascular Magnetic Resonance allows an accurate and reproducible quantification of left ventricular (LV) parameters. In Thalassemia major (TM) patients different normal LV values have been reported. In this study, the ranges for normal LV volumes, mass and ejection fraction normalized to the influence of body surface area (BSA), age and sex were established using the data of a large cohort of well-treated TM patients without myocardial iron overload.