Abstract #3217

In Vivo Sodium & Proton T1rho MR Imaging of Human Knee Cartilage at 3T

Chan Hong Moon¹, Jung-Hwan Kim¹, Tiejun Zhao², Xiang He¹, Bum-Woo Park¹, Kyongtae Ty Bae¹

¹Radiology, University of Pittsburgh, Pittsburgh, PA, United States; ²MR Research Support, Siemens Healthcare, Pittsburgh, PA, United States

We achieved consistent T2, T1rho, and sodium concentration measurements in knee cartilages from normal subjects using an in-house dual-tuned knee coil and in-house sequences at 3T. We believe MR-based physiological and metabolic measures of knee cartilage may play an important role as imaging biomarkers for early detection of knee ostheoarthritis.