Abstract #3203

Phosphocreatine & Acetylcarnitine in Skeletal Muscle During Exercise at 7T by Interleaved 31P & 1H-MRS

Katja Heinicke^1,2, Jackson Green^1,2, Ivan Dimitrov^3,4, Sergey Cheshkov³, Jimin Ren³, Craig R. Malloy³, Ronald G. Haller^1,2

¹Neuromuscular Center, Institute for Exercise & Environmental Medicine, Texas Health Presbyterian Hospital, Dallas, TX, United States; ²Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, United States; ³Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States; ⁴Philips Medical Systems, Cleveland, OH, United States

31P-MRS provides insight into muscle energy metabolism, and 1H-MRS offers direct measurement of intramyocellular lipid concentration and the concentration of acetylcarnitine which is important for characterizing mitochondrial function and integrity.