Abstract #3128

Dynamic Contrast-Enhanced Magnetic Resonance Imaging & Dynamic Contrast-Enhanced Computed Tomography of Primary Colorectal Cancer: Comparison of Test-Retest Agreement.

N. Jane Taylor¹, Ian C. Simcock¹, J. James Stirling¹, Aftab Khan², Rob Glynne-Jones², Anwar R. Padhani¹, Vicky J. Goh¹

¹Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex HA6 2RN, United Kingdom; ²Cancer Centre, Mount Vernon Hospital, Northwood, Middlesex HA6 2RN, United Kingdom

Assessment of tumour vascularisation and angiogenesis may provide prognostic and predictive information. This may be evaluated in primary colorectal cancer using dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) and dynamic contrast enhanced computed tomography (DCE-CT). Test-retest agreement is highly relevant to clinical utility but has not been compared in the same patient cohort to date. This prospective study was performed to compare the test-retest agreement of DCE-MRI and DCE-CT. Test-retest agreement for both techniques was adequate for clinical practice, and slightly better for DCE-CT than DCE-MRI for blood flow.