Abstract #3102

Automatic Image Registration of Lung CT & Hyperpolarized Helium-3 MRI Via Mutual Information of Proton MRI

Rob H. Ireland^1,2, James A. Swinscoe², Matthew Q. Hatton², Helen Marshall¹, Salma Ajraoui¹, Juan Parra-Robles¹, Jim M. Wild¹

¹Academic Radiology, University of Sheffield, Sheffield, S. Yorkshire, United Kingdom; ²Academic Clinical Oncology, University of Sheffield, Sheffield, S. Yorkshire, United Kingdom

This work demonstrates the feasibility of acquiring synchronous helium-3 lung ventilation and proton MRI in a single breath-hold imaging sequence for NSCLC patients. The availability of the concurrent proton MRI enables an automatic mutual information image registration of the helium-3 MRI to a lung CT. Such images could be valuable in the planning and evaluation of lung disease treatment.