Abstract #3043

Hypovascular Nodules Presented with Hypointensity on the Hepatobiliary Phase of Gd-EOB-DTPA Enhanced MRI in the Cirrhotic Liver: Implications for Developing Hypervascular Hepatocellular Carcinoma.

Tomoko Hyodo^1,2, Masahiro Okada¹, Yuki Kagawa¹, Sachiyo Kogita³, Seishi Kumano¹, Izumi Imaoka¹, Masatoshi Hori⁴, Kazunari Ishii¹, Yasuharu Imai³, Teruhito Mochizuki², Masatoshi Kudo⁵, Takamichi Murakami¹

¹Radiology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan; ²Diagnostic & Therapeutic Radiology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan; ³Gastroenterology, Ikeda Municipal Hospital, Ikeda, Osaka, Japan; ⁴Radiology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan; ⁵Gastroenterology & Hepatology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan

To clarify the signiﬁcance of hypovascular nodules presented with hypointensity on hepatobiliary phase of Gd-EOB-DTPA enhanced MRI in screening for hepatocellular carcinoma (HCC) in the cirrhotic liver, 122 hypovascular hepatic nodules with hypointensity on hepatobiliary phase in 54 patients were reviewed. The incidence rate of developing hypervascular HCC from such nodules was 32%. Patients with higher growth rate (GR) may have potential arterial hypervascularization, and GR of >2.8x10^-3 (tumor volume doubling time of < 355 days) may justifiy follow-up at short intervals.