Abstract #3034

3D Pulmonary Perfusion MRI with Whole-Chest Coverage, High Temporal & Isotropic Spatial Resolution

Kang Wang¹, Frank Korosec^1,2, Mark Schiebler², Christopher Francois², Scott Reeder^2,3, Thomas Grist², Reed Busse⁴, James Holmes⁴, Jean Brittain⁴, Nathan Artz¹, Sean Fain^1,3, Scott Nagle²

¹Medical Physics, University of Wisconsin-Madison, Madison, WI, United States; ²Radiology, University of Wisconsin-Madison, Madison, WI, United States; ³Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States; ⁴Applied Science Lab, GE Healthcare, Madison, WI, United States

MR pulmonary perfusion is well suited for studying the pulmonary circulation and understanding the physiology and pathology of the lung. However, MR pulmonary perfusion has been challenging due to the requirements for large spatial coverage, high temporal resolution, and high spatial resolution. The purpose of this study is to demonstrate the feasibility of obtaining high isotropic spatial resolution 3D dynamic pulmonary perfusion images of the whole chest with very high temporal resolution. The technique combines a previously developed Interleaved Variable Density sampling method with parallel imaging and Cartesian HYPR reconstruction.