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Abstract #2972

The Effect of Maternal Diabetes on Fetal Adiposity

Devasuda Anblagan1, Ruta Deshpande2, Alain Pitiot3, Carolyn Costigan1, Nia W. Jones2, George Bugg2, Peter Mansell2, Nick Raine Fenning4, Lopa Leach5, Penny A. Gowland1

1Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom; 2Nottingham University Hospitals NHS Trust, University of Nottingham, United Kingdom; 3School of Psychology, University of Nottingham, United Kingdom; 4School of Clinical Sciences, University of Nottingham, United Kingdom; 5School of Biomedical Sciences, University of Nottingham, Nottingham, United Kingdom


Macrosomia (birth weight > 90th percentile) is a common complication associated with diabetic pregnancies, and babies of mothers with established diabetes are at increased risk of developing Type 2 diabetes. The ability to measure fetal fat would be an invaluable tool in predicting adverse neonatal outcomes and managing diabetic pregnancies. We have considered two approaches to study the fetal fat composition using 1.5 T MRI: measuring fetal fat across the abdomen and measuring fetal fat across the whole body. We found that fetal fat volume is increased in the fetuses of diabetic mothers.