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Abstract #2943

Measurement of Field Inhomogeneity & Susceptibility Effects for Liver Iron Quantification in Patients with Iron Overload

Brian A. Taylor1, Ralf B. Loeffler1, Ruitian Song1, R. Jason Stafford2, Beth McCarville1, Jane S. Hankins3, Claudia M. Hillenbrand1

1Radiological Sciences, St. Jude Children's Research Hospital, Memphis, TN, United States; 2Imaging Physics, the University of Texas M. D. Anderson Cancer Center, Houston, TX, United States; 3Hematology, St. Jude Children's Research Hospital, Memphis, TN, United States


An autoregressive moving average (ARMA) model was used to calculate field inhomogeneities in T2* imaging of the liver in patients with iron overload. Comparisons were made between ARMA T2* measurements and T2* from monoexponential fits calibrated to liver iron content measurements via biopsy.