Galen D. Reed1, Adam B. Kerr2,
Peder E. Z. Larson, Eugene Ozhinsky, John Kurhanewicz, Daniel B. Vigneron
1Radiology & Biomedical
Imaging, University of California San Francisco, San Francisco, CA, United
States; 2Electrical Engineering, Stanford University, Palo Alto,
CA
Very Selective Saturation (VSS) pulses are critical for PRESS localized spectroscopy by providing outer volume suppression and reducing chemical shift artifacts. Since these bands are placed in parallel pairs, cosine modulation can be applied to excite two bands in a single pulse, thereby saving time in the suppression pulse train by eliminating redundant crusher gradients. This abstract demonstrates the design of an increased bandwidth dual band selective saturation pulse based on a convex optimization filter design (for optimizing selectivity) and biased-probability Monte Carlo root flipping algorithm (for minimizing computation time). These pulses were designed and tested in patient exams incorporating prostate MRSI