Localization by Nonlinear Phase Preparation & K-Space Trajectory Design (GradLoc)

Walter R.T. Witschey¹, Christian A. Cocosco¹, Daniel Gallichan¹, Gerrit Schultz¹, Hans Weber¹, Anna Masako Welz¹, Jrgen Hennig¹, Maxim Zaitsev¹

A technique is described for localization of MR signals from a target volume using nonlinear pulsed magnetic fields and spatial encoding trajectories designed using local k-space theory. In vivo human brain images were obtained using a custom quadrupolar gradient coil integrated with a whole-body 3 T MRI scanner to demonstrate localization in 3D T2*-weighted imaging.