Abstract #2764

Accurate T1 & T2 Quantification in Look-Locker 2D SSFP Imaging with Flip Angle Profile Correction

Mitchell Anthony Cooper^1,2, Thanh D. Nguyen³, Pascal Spincemaille³, Martin R. Prince³, Jonathan W. Weinsaft⁴, Yi Wang^1,3

¹Biomedical Engineering, Cornell University, Ithaca, NY, United States; ²Radiology, Weill Cornell Medical College , New York, United States; ³Radiology, Weill Cornell Medical College, New York, United States; ⁴Cardiology, Weill Cornell Medical College, New York, United States

In this study we investigated the accuracy of a new method to fit Look-Locker 2D SSFP data with flip angle profile correction. Utilizing the bloch equations and integrating over the flip angle profile, we were able to determine T1 with substantially lower error when compared to previous methods for SSFP T1 mapping sequences. We were able to accurately measure T1 and T2 in the thigh on a healthy volunteer cohort.