Abstract #2744

A Universal Sampling Scheme for the Method of Slopes (MoS) Allows for Rapid Simultaneous B1 & T1 Mapping in 2D

Sofia Chavez¹, Greg Stanisz^1,2

¹Imaging Research, Sunnybrook Research Institute, Toronto, ON, Canada; ²Medical Biophysics, University of Toronto, Toronto, ON, Canada

The Method of Slopes (MoS) has been proposed for simultaneous 3D B1 and T1 mapping. It uses 3D SPGR signal at different nominal flip angles (FAs). An extrapolation to signal is used to obtain B1. This extrapolation is valid if the sampled signal varies linearly with FA but the region of linearity varies spatially with B1. In this work, a method is proposed to overcome the inaccuracies in the extrapolation when the signal is not sampled in the linear region resulting in a universal sampling scheme which allows for a 2D signal calibration, extending the MoS to 2D applications.