Se Young Chun1,2, Timothy G. Reese2,3,
Bastien Guerin1,2, Ciprian Catana2,3, Georges El Fakhri1,2
1Division of Nuclear
Medicine & Molecular Imaging, Department of Radiology, Massachusetts
General Hospital, Boston, MA, United States; 2Radiology, Harvard
Medical School, Boston, MA, United States; 3Athinoula A. Martinos
Center for Biomedical Imaging, Department of Radiology, Massachusetts General
Hospital, Boston, MA, United States
Motion artifacts in PET becomes a key problem affecting image quality. Combined MR-PET provides a new opportunity to improve PET image quality with accurately estimated motion from simultaneously acquired tagged MR without increased radiation dose. Here we report progress in our in-vivo motion correction study, showing results from a free-breathing primate that demonstrates the feasibility of PET motion correction in simultaneous MR-PET. Our tagged MR based motion correction methods significantly reduced motion artifacts and noise as compared to no motion correction or gating. They achieved image qualities comparable to those of gating method with much longer (8x) acquisition.