WASSR Imaging of αvβ3 Targeted USPIO at 2.35T on U87 Mice Tumors : Feasibility Study

Jean-Sebastien Raynaud¹, Antony Lee¹, Xavier Violas¹, Robin Santus¹, Gaelle Louin¹, Isabelle Raynal¹, Philippe Robert¹, Marc Port¹, Claire Corot¹

In this study, we purpose to adapt a modified ORS sequence, WASSR (WAter Saturation Shift Referencing), initially applied on CEST contrast, to investigate in vitro and in vivo detection of a targeted USPIO in a clinical field.