In Vivo Human Brain T2* Mapping using 3D High Resolution Multiple Echo Susceptibility-Weighted Imaging at 7.0T

Zhongwei Zhang¹, Jens H. Jensen¹, Lin Tang¹, Yudong Zhu¹, Yulin Ge¹

Ultra-high-field strength MR has provided sophisticated imaging capability to improve the fundamental quantities underlying image resolution and contrast. This includes significantly increased susceptibility sensitivity to gray matter iron deposition. Its a worthwhile goal to acquire T2* mapping and phase mapping with high resolution because both types of information have the potential to assess iron content. The aim of this study was to investigate quantitative T2* measurements and phase information of in-vivo human brains using 3D multiple in-phase echo susceptibility-weighted MR Imaging (3D MIPE-SWI) at 7.0T. In addition, the feasibility of obtaining other quantitative informations was also explored.